The administration of plant-derived cannabis extracts is effective and well-tolerated in patients diagnosed with autism spectrum disorders (ASD), according to data published in the journal Scientific Reports.
Israeli investigators assessed the safety and efficacy of the daily administration of CBD-enriched cannabis oil (consisting of 30 percent CBD and 1.5 percent THC) in a cohort of 188 patients with ASD. Of those patients who continued treatment for six months and provided feedback to researchers, over 90 percent reported some level of symptomatic improvement — including reductions in restlessness, seizures, and rage attacks. Approximately one-third of respondents reported a reduction in their intake of other medications.
Authors concluded: “Cannabis as a treatment for autism spectrum disorders patients appears to be well-tolerated, safe and seemingly effective option to relieve symptoms, mainly: seizures, tics, depression, restlessness and rage attacks. … [W]e believe that double blind placebo-controlled trials are crucial for a better understanding of the cannabis effect on ASD patients.”
The results are consistent with those of a prior Israeli study which concluded that the daily administration of CBD-dominant extracts was associated with “overall improvement in behavior, anxiety, and communication” in autism patients.